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PNAS Liu GY, Doran KS, Lawrence T, Turkson N, Puliti M, Tissi L, Nizet V.  Sword and shield: Linked group B streptococcal -hemolysin/cytolysin and carotenoid pigment function to subvert phagocyte defense.  Proc Natl Acad Sci USA 2004; 101:14491-14496.  ABSTRACT  |  PDF  |  Press Release
Doran KS, Nizet V.  Molecular pathogenesis of neonatal group B streptococcal infection:  No longer in its infancy. Mol Microbiol 2004; 54:23-31.  ABSTRACT  |  PDF
PNAS Lewis A, Nizet V, Varki A.  Discovery and characterization of sialic acid O-acetylation in group B Streptococcus. Proc Natl Acad Sci USA 2004; 101:11123-11128.  ABSTRACT  |  PDF  |  Press Release
Hidalgo-Grass C, Dan-Goor M, Maly A, Eran Y, Kwinn LA, Nizet V, Ravins M, Jaffe J, Moses AE, Hanski E. Effect of a bacterial pheromone peptide on host chemokines in group A streptococcal necrotising soft-tissue infections.  Lancet 2004; 263: 696-703.  ABSTRACT  |  PDF
Aziz RK, Pabst MJ, Jeng A, Kansal R, Low DE, Nizet V, Kotb M. Invasive M1T1 group A Streptococcus undergoes an in vivo phase-shift to prevent proteolytic degradation of multiple virulence factors by SpeB. Mol Microbiol 2004;  51:123-134.  ABSTRACT  |  PDF
Liu GY, Nizet V.  Extracellular virulence factors of group B Streptococcus. Front Biosci 2004; 9: 1794-1802.  ABSTRACT  |  PDF
Bardan A, Nizet V, Gallo RL.  Antimicrobial peptides and the skin.  Expert Opin Biol Ther 2004; 4:543-549.  ABSTRACT  |  PDF
Doran K, Liu GY, Nizet V. Group B streptococcal -hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J Clin Invest 2003; 112:736-744.  ABSTRACTPDF Press Release
Nizet V, Gallo RL. Cathelicidins and innate immunity against invasive bacterial infection. Scand J Infect Dis 2003; 35:670-676.  ABSTRACT  |  PDF
Saitoh A, Beall B, Nizet V. Fulminant bacterial meningitis complicating sphenoid sinusitis. Ped Emerg Care 2003; 19:415-417.  PDF

Jeng A, Li Z, Sakota V, Datta V, Beall B, Nizet V. Molecular genetic analysis of a group A streptococcal operon encoding serum opacity factor and a novel fibronectin-binding protein, SfbX.  J Bacteriol 2003; 185:1208-1217.  ABSTRACT  | PDF

Gallo RL, Nizet V. Endogenous production of antimicrobial peptides in innate immunity and human disease. Curr Allergy Asthma Rep 2003; 3:402-409. ABSTRACT | PDF
Zaiou M, Nizet V, Gallo RL. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol 2003; 120:810-816.  ABSTRACT  |  PDF
Kristian SA, Lauth X, Nizet V, Gtz F, Neumeister B, Peschel A, Landmann R.  Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage model. J Infect Dis 2003; 188:414-23. ABSTRACT | PDF
Cramer T, Yamanashi Y, Clausen BE, Forster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein G, Gerber H-P, Ferrara N, Johnson RS.   HIF-1alpha is essential for myeloid cell mediated inflammation.  Cell 2003; 112:645-657. ABSTRACT  |  PDF  |  Press Release
Kansal RG, Nizet V, Jeng A, Chaung W-J, Kotb M. Selective modulation of superantigen-induced responses by streptococcal cysteine protease. J Infect Dis 2003; 187:398-407.  ABSTRACT  |  PDF

Nizet V.  Streptococcal -hemolysins:  Genetics and role in disease pathogenesis.  Trends Microbiol 2002 10:575-580. ABSTRACT  |  PDF

Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V.  Group B streptococcal -hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8.  J Infect Dis 2002 185:196-203.  ABSTRACTPDF


Humar D, Datta V, Bast DJ, Beall B, De Azavedo JC, Nizet V.  Streptolysin S and necrotizing infections produced by group G Streptococcus.  Lancet  2002 359:124-9.  ABSTRACT | PDF | Press Release


Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT. Cellular activation, phagocytosis, and bactericidal activity against group B Streptococcus involve parallel myeloid-differention factor 88-dependent and independent signaling pathways. J Immunol 2002 169: 3970-3977.  ABSTRACT  |  PDF

The Pediatric Infectious Diseases Society Annual Awards, 2002.  Pediatr Infect Dis J 2000  21:803-806. PDF
Ring A, Depnering C, Pohl J, Nizet V, Shenep JL, Stremmel W.  Synergistic action of nitric oxide release from murine macrophages caused by group B streptococcal cell wall and -hemolysin/cytolysin.  J Infect Dis 2002 186:1518-1521. ABSTRACT  |  PDF

Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V.  Late-onset group B streptococcal infection in identical twins: insight to disease pathogenesis.  J Perinatol 2002 22:326-30.  ABSTRACT  |  PDF 
Nizet V, Gallo RL.  Surviving innate immunity (commentary).  Trends Microbiol  2002 10:358-359.  PDF

Fuller JD, Camus A, Duncan CL, Nizet V, Bast DJ, Thune RL, Low DE, De Azavedo JCS.  Discovery of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun 2002; 70: 5730-5739.  ABSTRACT  |  PDF

Ring A, Braun JS, Pohl J, Nizet V, Stremmel W, Shenep JL.   Group B streptococcal -hemolysin induces mortality and liver injury in experimental sepsis.   J Infect Dis 2002 1745-1753.  ABSTRACT  |  PDF


Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P. Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem 2002 277:5030-5039.  ABSTRACT  |  PDF

Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 2001 414:454-7.  ABSTRACT  |  PDF  |  Press Release

Pritzlaff CA, Chang JC, Kuo SP, Tamura GS, Rubens CE, Nizet V.  Genetic basis for the -haemolytic/ cytolytic activity of group B StreptococcusMol Microbiol 2001 39:236-47.  ABSTRACTPDF
Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith J, Schromm A, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT.  Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.  J Immunol 2001 167:7069-76.  ABSTRACT  |  PDF

Ballon-Landa GR, Gherardi G, Beall B, Krosner S, Nizet V.  Necrotizing fasciitis due to penicillin-resistant Streptococcus pneumoniae: case report and review of the literature.  J Infect 2001 42:272-7.  ABSTRACT  | PDF
Dorschner RA, Pestonjamasp V, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol 2001 117:91-7.  ABSTRACT  |  PDF
Fuller JD, Bast DJ, Nizet V, Low DE, de Azavedo JC.  Streptococcus iniae virulence is associated with a distinct genetic profile.  Infect Immun 2001 69:1994-2000.  ABSTRACT  |  PDF

Puliti M, Nizet V, von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L.  Severity of group B streptococcal arthritis is correlated with -hemolysin expression.  J Infect Dis 2000 182:824-32.  ABSTRACT  |  PDF

Nizet V, Beall B, Bast DJ, Datta V, Kilburn L, Low DE, De Azavedo JC. Genetic locus for streptolysin S production by group A streptococcus.  Infect Immun 2000 68:4245-54.  ABSTRACT  |  PDF
Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL. Group B streptococcal -hemolysin induces nitric oxide production in murine macrophages.  J Infect Dis 2000 182:150-7.  ABSTRACT  |  PDF
Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M.  Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells.  Infect Immun 2000 68:637-43.  ABSTRACT  |  PDF

Nizet V, Ferrieri P, Rubens CE.  Molecular pathogenesis of group B streptococcal disease in newborns.  In:  Streptococcal Infections: Clinical Aspects, Microbiology and Molecular Pathogenesis (DL Stevens, EL Kaplan, eds.).  Oxford University Press, New York, pp. 180-221. 2000.  PDF

Nizet V, Rubens CE.  Pathogenic mechanisms and virulence factors of group B streptococci.  In:  The Gram-Positive Pathogens (VA Fischetti, RP Novick, JJ Ferretti, DA Portnoy, JI Rood, eds.). ASM Press. Washington, D.C., pp. 125-136.  2000.  PDF

Gibson RL, Nizet V, Rubens CE. Group B streptococcal -hemolysin promotes injury of lung microvascular endothelial cells. Pediatr Res 1999 45:626-34.  ABSTRACT  | PDF

Nizet V, Smith AL, Sullam PM, Rubens CE.  A simple microtiter plate screening assay for bacterial invasion or adherence.  Meth Cell Sci 1998 20:107-111.  PDF
Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. Invasion of brain microvascular endothelial cells by group B streptococci.  Infect Immun 1997 65:5074-81.  ABSTRACT  |  PDF

Nizet V, Gibson RL, Rubens CE. The role of group B streptococci -hemolysin expression in newborn lung injury. Adv Exp Med Biol 1997 418:627-30.  ABSTRACT
Infectious Diseases in
                Clinical Practice Nizet V, Brogan TV. Enterococcal necrotizing fasciitis complicating elective hernia repair in an infant. Infect Dis Clin Pract 1996; 5:76-8.  PDF
Nizet V, Gibson RL, Chi EY, Framson PE, Hulse M, Rubens CE. Group B streptococcal -hemolysin expression is associated with injury of lung epithelial cells.  Infect Immun 1996 64:3818-26.  ABSTRACT  |  PDF

Mills WJ, Mosca VS, Nizet V.  Orthopaedic manifestations of invasive group A streptococcal infections complicating primary varicella.  J Pediatr Orthop 1996 16:522-8.   ABSTRACT  PDF   

Brogan TV, Nizet V, Waldhausen JH.  Streptococcal skin infections (letter).  N Engl J Med 1996 334:1478.  PDF
Nizet V, Colina KF, Almquist JR, Rubens CE, Smith AL. A virulent nonencapsulated Haemophilus influenzae. J Infect Dis 1996 Jan;173(1):180-6.  ABSTRACT  |   PDF 
Brogan TV, Nizet V, Waldhausen JH, Rubens CE, Clarke WR. Group A streptococcal necrotizing fasciitis complicating primary varicella: a series of fourteen patients. Pediatr Infect Dis J 1995 14:588-94.  ABSTRACT  |  PDF  


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