Nizet Lab: Earlier Publications


	*Publications up to 2002 ...*

	Nizet V. Streptococcal ß-hemolysins: Genetics and role in disease pathogenesis. Trends Microbiol 2002 10:575-580. ABSTRACT \| PDF
	Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. Group B streptococcal ß-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J Infect Dis 2002 185:196-203. ABSTRACT \| PDF
	Humar D, Datta V, Bast DJ, Beall B, De Azavedo JC, Nizet V. Streptolysin S and necrotizing infections produced by group G Streptococcus. Lancet 2002 359:124-9. ABSTRACT \| PDF \| Press Release
	Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT. Cellular activation, phagocytosis, and bactericidal activity against group B Streptococcus involve parallel myeloid-differention factor 88-dependent and independent signaling pathways. J Immunol 2002 169: 3970-3977. ABSTRACT \| PDF
	The Pediatric Infectious Diseases Society Annual Awards, 2002. Pediatr Infect Dis J 2000 21:803-806. PDF
	Ring A, Depnering C, Pohl J, Nizet V, Shenep JL, Stremmel W. Synergistic action of nitric oxide release from murine macrophages caused by group B streptococcal cell wall and ß-hemolysin/cytolysin. J Infect Dis 2002 186:1518-1521. ABSTRACT \| PDF
	Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V. Late-onset group B streptococcal infection in identical twins: insight to disease pathogenesis. J Perinatol 2002 22:326-30. ABSTRACT \| PDF
	Nizet V, Gallo RL. Surviving innate immunity (commentary). Trends Microbiol 2002 10:358-359. PDF
	Fuller JD, Camus A, Duncan CL, Nizet V, Bast DJ, Thune RL, Low DE, De Azavedo JCS. Discovery of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun 2002; 70: 5730-5739. ABSTRACT \| PDF
	Ring A, Braun JS, Pohl J, Nizet V, Stremmel W, Shenep JL. Group B streptococcal ß-hemolysin induces mortality and liver injury in experimental sepsis. J Infect Dis 2002 1745-1753. ABSTRACT \| PDF
	Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P. Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem 2002 277:5030-5039. ABSTRACT \| PDF
	Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 2001 414:454-7. ABSTRACT \| PDF \| Press Release
	Pritzlaff CA, Chang JC, Kuo SP, Tamura GS, Rubens CE, Nizet V. Genetic basis for the ß-haemolytic/ cytolytic activity of group B Streptococcus. Mol Microbiol 2001 39:236-47. ABSTRACT \| PDF
	Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith J, Schromm A, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT. Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. J Immunol 2001 167:7069-76. ABSTRACT \| PDF
	Ballon-Landa GR, Gherardi G, Beall B, Krosner S, Nizet V. Necrotizing fasciitis due to penicillin-resistant Streptococcus pneumoniae: case report and review of the literature. J Infect 2001 42:272-7. ABSTRACT \| PDF
	Dorschner RA, Pestonjamasp V, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol 2001 117:91-7. ABSTRACT \| PDF
	Fuller JD, Bast DJ, Nizet V, Low DE, de Azavedo JC. Streptococcus iniae virulence is associated with a distinct genetic profile. Infect Immun 2001 69:1994-2000. ABSTRACT \| PDF
	Puliti M, Nizet V, von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L. Severity of group B streptococcal arthritis is correlated with ß-hemolysin expression. J Infect Dis 2000 182:824-32. ABSTRACT \| PDF
	Nizet V, Beall B, Bast DJ, Datta V, Kilburn L, Low DE, De Azavedo JC. Genetic locus for streptolysin S production by group A streptococcus. Infect Immun 2000 68:4245-54. ABSTRACT \| PDF
	Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL. Group B streptococcal ß-hemolysin induces nitric oxide production in murine macrophages. J Infect Dis 2000 182:150-7. ABSTRACT \| PDF
	Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M. Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells. Infect Immun 2000 68:637-43. ABSTRACT \| PDF
	Nizet V, Ferrieri P, Rubens CE. Molecular pathogenesis of group B streptococcal disease in newborns. In: Streptococcal Infections: Clinical Aspects, Microbiology and Molecular Pathogenesis (DL Stevens, EL Kaplan, eds.). Oxford University Press, New York, pp. 180-221. 2000. PDF
	Nizet V, Rubens CE. Pathogenic mechanisms and virulence factors of group B streptococci. In: The Gram-Positive Pathogens (VA Fischetti, RP Novick, JJ Ferretti, DA Portnoy, JI Rood, eds.). ASM Press. Washington, D.C., pp. 125-136. 2000. PDF
	Gibson RL, Nizet V, Rubens CE. Group B streptococcal ß-hemolysin promotes injury of lung microvascular endothelial cells. Pediatr Res 1999 45:626-34. ABSTRACT \| PDF
	Nizet V, Smith AL, Sullam PM, Rubens CE. A simple microtiter plate screening assay for bacterial invasion or adherence. Meth Cell Sci 1998 20:107-111. PDF
	Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. Invasion of brain microvascular endothelial cells by group B streptococci. Infect Immun 1997 65:5074-81. ABSTRACT \| PDF
	Nizet V, Gibson RL, Rubens CE. The role of group B streptococci ß-hemolysin expression in newborn lung injury. Adv Exp Med Biol 1997 418:627-30. ABSTRACT
	Nizet V, Gibson RL, Chi EY, Framson PE, Hulse M, Rubens CE. Group B streptococcal ß-hemolysin expression is associated with injury of lung epithelial cells. Infect Immun 1996 64:3818-26. ABSTRACT \| PDF
	Mills WJ, Mosca VS, Nizet V. Orthopaedic manifestations of invasive group A streptococcal infections complicating primary varicella. J Pediatr Orthop 1996 16:522-8. ABSTRACT
	Brogan TV, Nizet V, Waldhausen JH. Streptococcal skin infections (letter). N Engl J Med 1996 334:1478.
	Nizet V, Colina KF, Almquist JR, Rubens CE, Smith AL. A virulent nonencapsulated Haemophilus influenzae. J Infect Dis 1996 Jan;173(1):180-6. ABSTRACT
	Brogan TV, Nizet V, Waldhausen JH, Rubens CE, Clarke WR. Group A streptococcal necrotizing fasciitis complicating primary varicella: a series of fourteen patients. Pediatr Infect Dis J 1995 14:588-94. ABSTRACT

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	Nizet V. Streptococcal ß-hemolysins: Genetics and role in disease pathogenesis. Trends Microbiol 2002 10:575-580. ABSTRACT \| PDF
	Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. Group B streptococcal ß-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J Infect Dis 2002 185:196-203. ABSTRACT \| PDF
	Humar D, Datta V, Bast DJ, Beall B, De Azavedo JC, Nizet V. Streptolysin S and necrotizing infections produced by group G Streptococcus. Lancet 2002 359:124-9. ABSTRACT \| PDF \| Press Release
	Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT. Cellular activation, phagocytosis, and bactericidal activity against group B Streptococcus involve parallel myeloid-differention factor 88-dependent and independent signaling pathways. J Immunol 2002 169: 3970-3977. ABSTRACT \| PDF
	The Pediatric Infectious Diseases Society Annual Awards, 2002. Pediatr Infect Dis J 2000 21:803-806. PDF
	Ring A, Depnering C, Pohl J, Nizet V, Shenep JL, Stremmel W. Synergistic action of nitric oxide release from murine macrophages caused by group B streptococcal cell wall and ß-hemolysin/cytolysin. J Infect Dis 2002 186:1518-1521. ABSTRACT \| PDF
	Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V. Late-onset group B streptococcal infection in identical twins: insight to disease pathogenesis. J Perinatol 2002 22:326-30. ABSTRACT \| PDF
	Nizet V, Gallo RL. Surviving innate immunity (commentary). Trends Microbiol 2002 10:358-359. PDF
	Fuller JD, Camus A, Duncan CL, Nizet V, Bast DJ, Thune RL, Low DE, De Azavedo JCS. Discovery of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun 2002; 70: 5730-5739. ABSTRACT \| PDF
	Ring A, Braun JS, Pohl J, Nizet V, Stremmel W, Shenep JL. Group B streptococcal ß-hemolysin induces mortality and liver injury in experimental sepsis. J Infect Dis 2002 1745-1753. ABSTRACT \| PDF
	Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P. Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem 2002 277:5030-5039. ABSTRACT \| PDF
	Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 2001 414:454-7. ABSTRACT \| PDF \| Press Release
	Pritzlaff CA, Chang JC, Kuo SP, Tamura GS, Rubens CE, Nizet V. Genetic basis for the ß-haemolytic/ cytolytic activity of group B Streptococcus. Mol Microbiol 2001 39:236-47. ABSTRACT \| PDF
	Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith J, Schromm A, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT. Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. J Immunol 2001 167:7069-76. ABSTRACT \| PDF
	Ballon-Landa GR, Gherardi G, Beall B, Krosner S, Nizet V. Necrotizing fasciitis due to penicillin-resistant Streptococcus pneumoniae: case report and review of the literature. J Infect 2001 42:272-7. ABSTRACT \| PDF
	Dorschner RA, Pestonjamasp V, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol 2001 117:91-7. ABSTRACT \| PDF
	Fuller JD, Bast DJ, Nizet V, Low DE, de Azavedo JC. Streptococcus iniae virulence is associated with a distinct genetic profile. Infect Immun 2001 69:1994-2000. ABSTRACT \| PDF
	Puliti M, Nizet V, von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L. Severity of group B streptococcal arthritis is correlated with ß-hemolysin expression. J Infect Dis 2000 182:824-32. ABSTRACT \| PDF
	Nizet V, Beall B, Bast DJ, Datta V, Kilburn L, Low DE, De Azavedo JC. Genetic locus for streptolysin S production by group A streptococcus. Infect Immun 2000 68:4245-54. ABSTRACT \| PDF
	Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL. Group B streptococcal ß-hemolysin induces nitric oxide production in murine macrophages. J Infect Dis 2000 182:150-7. ABSTRACT \| PDF
	Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M. Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells. Infect Immun 2000 68:637-43. ABSTRACT \| PDF
	Nizet V, Ferrieri P, Rubens CE. Molecular pathogenesis of group B streptococcal disease in newborns. In: Streptococcal Infections: Clinical Aspects, Microbiology and Molecular Pathogenesis (DL Stevens, EL Kaplan, eds.). Oxford University Press, New York, pp. 180-221. 2000. PDF
	Nizet V, Rubens CE. Pathogenic mechanisms and virulence factors of group B streptococci. In: The Gram-Positive Pathogens (VA Fischetti, RP Novick, JJ Ferretti, DA Portnoy, JI Rood, eds.). ASM Press. Washington, D.C., pp. 125-136. 2000. PDF
	Gibson RL, Nizet V, Rubens CE. Group B streptococcal ß-hemolysin promotes injury of lung microvascular endothelial cells. Pediatr Res 1999 45:626-34. ABSTRACT \| PDF
	Nizet V, Smith AL, Sullam PM, Rubens CE. A simple microtiter plate screening assay for bacterial invasion or adherence. Meth Cell Sci 1998 20:107-111. PDF
	Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. Invasion of brain microvascular endothelial cells by group B streptococci. Infect Immun 1997 65:5074-81. ABSTRACT \| PDF
	Nizet V, Gibson RL, Rubens CE. The role of group B streptococci ß-hemolysin expression in newborn lung injury. Adv Exp Med Biol 1997 418:627-30. ABSTRACT
	Nizet V, Gibson RL, Chi EY, Framson PE, Hulse M, Rubens CE. Group B streptococcal ß-hemolysin expression is associated with injury of lung epithelial cells. Infect Immun 1996 64:3818-26. ABSTRACT \| PDF
	Mills WJ, Mosca VS, Nizet V. Orthopaedic manifestations of invasive group A streptococcal infections complicating primary varicella. J Pediatr Orthop 1996 16:522-8. ABSTRACT
	Brogan TV, Nizet V, Waldhausen JH. Streptococcal skin infections (letter). N Engl J Med 1996 334:1478.
	Nizet V, Colina KF, Almquist JR, Rubens CE, Smith AL. A virulent nonencapsulated Haemophilus influenzae. J Infect Dis 1996 Jan;173(1):180-6. ABSTRACT
	Brogan TV, Nizet V, Waldhausen JH, Rubens CE, Clarke WR. Group A streptococcal necrotizing fasciitis complicating primary varicella: a series of fourteen patients. Pediatr Infect Dis J 1995 14:588-94. ABSTRACT