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Manuscripts Now Accepted or In Press

Scientific Data Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson C, Lamsa A, Seif Y, Dillon N,Vrbanac A, Sugie J, Dahesh S, Monk J, Dorrestein P, Pogliano J, Knight R, Nizet V, Palsson B, Feist A. Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media.  Sci Data 2019
Journal of Innate Immunity Patras KA, Ha AD, Rooholfada E, Olson J, RamachandraRao SP, Lin AE, Nizet V. Augmentation of urinary lactoferrin enhances host innate immune clearance of uropathogenic E. coliJ Innate Immun 2019
Antimicrobial Agents and
                Chemotherapy Dahesh S, Wong B, Nizet V, Sakoulas G.  Treatment of multi-drug resistant vancomycin-resistant Enterococcus faecium hardware-associated vertebral osteomyelitis with oritavancin plus ampicillin. Antimicrob Agents Chemother 2019


Submitted Manuscripts in Peer Review



Munguia J, Lin L, Olson J, Nonejuie P, Gallo RL, Adams MD, Kirkup BC, Pogliano J, Zurawski DV, Nizet V. Outer membrane lipid modifying protein VacJ contributes to antimicrobial peptide resistance and virulence of multidrug-resistant Acinetobacter baumannii.

Pence MA, Malone C, van Sorge NM, Horswill AR, Nizet V.  The metalloprotease aureolysin is not essential for cathelicidin resistance or virulence of methicillin-resistant Staphylococcus aureus

Pashangeh S, Shekarforoush SS, Aminlari M, Hosseinzadeh S, Nizet V, Dahesh S, Rahmdel S.  Molecular characteristics of histamine producing and degrading staphylococci isolated from goats and sheep milk.

Henningham A, Davies MR, Chan A, Thompson LF, Stewart C, Buffalo CZ, Corriden R, McIntyre L, Olson J, Ghosh P, Boss GR, Walker MJ, Cole JN, Nizet V. The conserved surface-associated 5′-nucleotidase of group A Streptococcus is a vaccine antigen that protects against systemic infection.

Sun J, LaRock DL, Kimmey JM, Olson J, Jiang Z, O’Donoghue AJ, Nizet V, LaRock CN. Pseudomonas aeruginosa proteolytic activation of IL-1β drives pathological inflammation

Sakoulas G, Murray B, Askarian F, Nizet V. Ertapenem and cefazolin synergism in methicillin-susceptible Staphylococcus aureus with type A beta-lactamase.

LaRock DL, Sands J, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN.  Inflammasome inhibition blocks cardiac glycoside cellular toxicity.

Corriden R, Döhrmann S, Flores R, Denholtz M, Catteau L, Olson J, Chen A, Carlin AF, Nizet V.   Free fatty acids enhance formation of neutrophil extracellular traps.

Rivera-Hernandez T, Carnathan D, Jones S, Cork A, Davies M, Moyle P, Toth I, Batzloff M, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. An experimental group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a non-human primate model.

Cohen-Katsenelson K, Stender JD, Uchiyama S, Grezchnik AT, Nizet V, Glass CK, Newton AC. PH domain leucine rich repeat protein phosphatase 1 (PHLPP1) counter-regulates STAT1-mediated inflammatory signaling.

Quinn RA, Melnik AV, Vrbanac A, Patras KA, Christy M, Bodai Z, Belda-Ferre P, Aksenov A, Tripathi A, Chung LK, Humphrey G, Microsoft Word - Extended Data.docx Panitchpakdi M, Weldon K, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Downes M, Fu T, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng J, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Evans RM, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Nizet V, Knight R, Dorrestein PC. Global chemical impacts of the microbiome include unique bile acid conjugates that stimulate FXR.

Escajadillo T, Popov LM, Dahesh S, Carette JE, Nizet V. Sterol regulatory element binding protein-2 (SREBP-2) influences host cell susceptibility to the bacterial pore-forming toxin streptolysin O.

Dillon N, Holland M, Tsunemoto H, Hancock B, Cornax I, Pogliano J, Sakoulas G, Nizet V. Dual bacterial translation inhibitors azithromycin and minocycline demonstrate synergy against multidrug-resistant Acinetobacter baumannii.

Sun J, Uchiyama S, Olson J, Cornax I, Ando N, Kohno Y, Kyaw M, Aguilar B, Haste NM, Rose WE, Sakoulas G, Marth JD, Nizet V.  Repurposed drugs block toxin-driven platelet clearance by the hepatic Ashwell-Morell receptor to clear Staphylococcus aureus bacteremia.

Machado H, Weng L, Dillon N, Seif Y, Holland M, Pekar J, Monk J, Nizet V, Palsson B, Feist A.  A defined minimal medium for systems analyses of Staphylococcus aureus reveals strain-specific metabolic requirements.

Denholtz M, Zhu Y, He, Z, Lu H, Isoda T, Döhrmann S, Nizet V, Murre C.  Upon microbial challenge human neutrophils undergo rapid changes in nuclear architecture to orchestrate an immediate inflammatory gene program.

Gomez Toledo A, Golden G, Rosa-Campos A, Cuello H, Sorrentino J, Lewis N, Varki N, Nizet V, Smith JW, Esko JD. Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis.

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