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Joshua Olson Staff Research Associate |
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Originally from Dinuba,
California, Joshua received his B.S. in Biochemistry and
Molecular
Biology from UC Santa Barbara. After graduation Joshua
spent two
years working at the Sanford-Burnham Research Institution in
Santa
Barbara, first in the laboratory of Dr. Erkki Ruoslahti on
Bcl-2
protein and apoptosis, then in the laboratory of Jamey Marth
on
different glycobiological interactions that influence
adaptive immunity. Joshua currently contributes to multiple ongoing research projects in the laboratory, with a particular focus on animal models of infection and inflammation. One major goal is the pharmacological augmentation of HIF as a strategy to boosting innate immunity cell function, prevent bacterial infection and help support cutaneous wound healing. Another project include analyses of bacterial glycans and their interaction with host innate immune system, with an eye toward novel antibiotic approaches and vaccine development. Finally, Joshua is seeking to develop more accurate and informative in vivo models of pneumonia with Staphylococcus aureus and other human pathogens to allow analysis of virulence factors, innate immunity and anti-infective treatment strategies. |