Satoshi Uchiyama, MD, PhD
Assistant Project Scientist |
Home | Research | People | Publications | News | Collaborations | Contact | Calendar |
Satoshi was born in
Niigata, Japan and completed his medical school training
and pediatric residency at Niigata University School of
Medicine, briefly working as a neonatologist
thereafter. In 2006, Satoshi received a grant from
the Yoshida Scholarship Foundation to come to America for
basic science research training, landing him for his first
stint in our laboratory. During these four years,
Satoshi completed multiple projects related to GBS and
pneumococcal pathogenesis, bacterial penetration of the
blood-brain barrier, Siglec receptors in neutrophil
function, and the hepatic Ashwell-Morell receptor in
modulating the coagulopathy of sepsis. His efforts
and publications earned him the PhD degree from his home
university. In 2010, Satoshi joined the laboratory
of (Nizet Lab alum) Annelies
Zinkernagel at the University of Zurich for
postdoctoral training on GAS pathogenesis, Toll-like
receptor signaling, and M protein-fibrinogen
interactions. Satoshi then received a Marie Curie
Intra-European Fellowship to initiate his own research
group at the Helmholtz
Centre for Infection Research in Braunschweig,
Germany. There his laboratory studied the role of
GAS virulence factors in modulating pathogen escape for
autophagy pathways and intracellular killing. In 2015,
Satoshi was recruited back to the Research Faculty here at
UCSD to spearhead our laboratories efforts on new projects
related to the glycobiology of host-pathogen dynamics
mediating the coagulopathy and vaculopathy of sepsis -
work that sprung from his earlier research in the
laboratory and will involve GAS, GBS, S. aureus
interactions with host platelets, clotting factors and
endothelium. This research is a collaboration with
the group of Jamey
Marth at UC Santa Barbara. |
|