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Accepted Manuscripts in Press

Journal of
                Antibiotics Reynolds KA, Dahesh S, Nizet V, Moore BS.  Isolation and structure elucidation of taromycin B from the activated taromycin biosynthetic gene cluster.  J Antibiot 2017
PLoS Pathogens Guichard A, Jain P, Moayeri M, Schwarz R, Chin S, Zhu L, Cruz-Moreno B, Liu JZ, Aguilar B, Hollands A, Leppla SH, Nizet V, Bier E.  Anthrax edema toxin disrupts distinct dteps in Rab11-dependent junctional transport.  PLoS Pathog 2017
Future Microbiology Valderrama JA, Nizet V. Group A Streptococcus encounters with host macrophages.  Future Microbiol 2017
PNAS Thamphiwatana S*, Angsantikul P*, Escajadillo T*, Zhang Q, Olson J, Luk BT, Zhang S, Fang RH, Gao W, Nizet V, Zhang L. Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management.


Submitted Manuscripts in Peer Review



Munguia J, Lin L, Olson J, Nonejuie P, Gallo RL, Adams MD, Kirkup BC, Pogliano J, Zurawski DV, Nizet V. Outer membrane lipid modifying protein VacJ contributes to antimicrobial peptide resistance and virulence of multidrug-resistant Acinetobacter baumannii.

Lawrence SM, Corriden R, Nizet V.  The lifecycle of a neutrophil, Part 1: Ontogeny, granulopoiesis and homeostasis .

Lawrence SM, Corriden R, Nizet V.  The lifecycle of a neutrophil, Part 2: Effector functions, cell death regulation and roles in human disease.

Pence MA, Malone C, van Sorge NM, Horswill AR, Nizet V.  The metalloprotease aureolysin is not essential for cathelicidin resistance or virulence of methicillin-resistant Staphylococcus aureus

Kumaraswamy M, Ashlock B, Nizet V, Crotty Alexander L.  Flu Gone Bad:  Asthma, influenza and secondary bacterial pneumonia precipitating diabetic ketoacidosis in a morbidly obese diabetic male.

Ugolini F, Andreoni F, Keller N, Neff A, Nizet V, Hollands A, Marques-Maggio E, Zinkernagel A, Schuepbach R.  Attenuation of streptokinase-mediated virulence in Streptococcus (SDSE) necrotizing fasciitis by immunoglobulin.

Mesci P, Macia A, LaRock CN, Tejwani L, Fernandes IR, Suarez NA, Zanotto P, Beltrão-Braga CB,  Nizet V,  Muotri AR. Modeling neuro-immune interactions during Zika virus infection.

van den Broek M, Claes I, Nizet V, Lebeer S.  Antimicrobial activity of lactobacilli and lactic acid against key otitis media pathogens.

Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD.  Recurrent Salmonella infection progressively disables a homeostatic mechanism of host protection.

Caffrey AR, Timbrook TT, Ali SR, Nizet V, Sakoulas G.  Proton pump inhibitors do not influence clinical outcomes in patients with Staphylococcus aureus bacteremia.

Monogue M, Sakoulas G, Nizet V, Nicolau D.  Humanized exposures of a β-lactam-β-lactamase inhibitor, tazobactam, versus non-β-lactam-β-lactamase inhibitor, avibactam, with or without colistin, against Acinetobacter baumannii in murine thigh and lung infection models.

Choe D,  Szubin R,  Dahesh S,  Cho; S, Nizet V, Palsson BO, Cho BK. Genome-scale analysis of community-acquired methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis mechanisms and antibiotic resistance.

Askarian F, Lapek JD, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh PJ, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M.  Staphylococcus aureus membrane-derived vesicles confer immune resistance and proinflammatory properties and serve as a vaccination platform.

Sakoulas G, Kumaraswamy M, Kousha A, Nizet V.  Interaction of antibiotics with innate host defense factors against Salmonella enterica serotype Newport.

Alisson-Silva F, Liu J, Diaz S, Deng L, Gareau M, Chen X, Nizet V, Varki N, Barrett K, Varki A. Human evolutionary loss of epithelial Neu5Gc expression and the species-specific susceptibility to cholera.

Liu JZ, Ali SR, Bier E, Nizet V.  Innate immune interactions between Bacillus anthracis and host neutrophils.

Corriden R, Liu R, Shin S, Sinha R, Pogliano J, Pogliano K, Griffin J, Nizet V, Gupta N.  MDSCH79797 improves outcomes in murine E. coli pneumonia by augmentation of neutrophil antibacterial activity and direct antibacterial action.

Britt N, Tirmizi S, Ritchie D, Topal J, McManus D, Nizet V, Casabar E, Sakoulas G. Telavancin for refractory methicillin-resistant Staphylococcus aureus bacteremia in intermittent hemodialysis recipients and the importance of synergy with human cathelicidin LL-37.

Gupta N, Sinha R, Krasnodembskaya A, Xu X, Nizet V, Matthay MA, Griffin JH. The TLR4-PAR1 axis regulates bone marrow mesenchymal stromal cell survival and therapeutic capacity in experimental bacterial pneumonia.

Mascuch SJ, Boudreau PD, Carland TM, Pierce NT, Olson J, Hensler ME, Choi H, Campanale J, Hamdoun A, Nizet V, Gerwick WH, Gaasterland T, Gerwick L. The marine natural product honaucin A attenuates inflammation by activating the Nrf2-ARE pathway.

Askarian F, Wagner T, Johannessen M, Nizet V. Modulation of inflammatory responses by Staphylococcus aureus mediated through pattern recognition receptor signaling.

Pashangeh S, Shekarforoush SS, Aminlari M, Hosseinzadeh S, Nizet V, Dahesh S, Rahmdel S.  Molecular characteristics of histamine producing and degrading staphylococci isolated from goats and sheep milk.

Henningham A, Davies MR, Chan A, Thompson LF, Stewart C, Buffalo CZ, Corriden R, McIntyre L, Olson J, Ghosh P, Boss GR, Walker MJ, Cole JN, Nizet V. The conserved surface-associated 5′-nucleotidase of group A Streptococcus is a vaccine antigen that
protects against systemic infection.

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