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Manuscripts Now Accepted or In Press

Engineering Kim JK, Uchiyama S, Gong H, Stream A, Zhang L, Nizet V. Engineered Biomimetic Platelet membrane-coated nanoparticles block Staphylococcus aureus cytotoxicity and protect against lethal systemic infection.  Engineering 2020
Journal of Experimental
                Medicine Marki A, Buscher K, Lorenzini C, Meyer M, Saigusa R, Fan Z, Yeh YT, Hartmann N, Golden G, Dan J, Kiosses W, Ganesan R, Winkels H, Orecchioni M, McArdle S, Mikulski Z, Altman Y, Bui J, Kronenberg M, Esko J, Chien S, Nizet V, Smalley D, Roth J, Ley K. Elongated neutrophil-derived structures (ENDS) are novel blood borne microparticles formed by rolling neutrophils during sepsis. J Exp Med 2020


Submitted Manuscripts in Peer Review



Munguia J, Lin L, Olson J, Nonejuie P, Gallo RL, Adams MD, Kirkup BC, Pogliano J, Zurawski DV, Nizet V. Outer membrane lipid modifying protein VacJ contributes to antimicrobial peptide resistance and virulence of multidrug-resistant Acinetobacter baumannii.

Pence MA, Malone C, van Sorge NM, Horswill AR, Nizet V.  The metalloprotease aureolysin is not essential for cathelicidin resistance or virulence of methicillin-resistant Staphylococcus aureus

Pashangeh S, Shekarforoush SS, Aminlari M, Hosseinzadeh S, Nizet V, Dahesh S, Rahmdel S.  Molecular characteristics of histamine producing and degrading staphylococci isolated from goats and sheep milk.

Henningham A, Davies MR, Chan A, Thompson LF, Stewart C, Buffalo CZ, Corriden R, McIntyre L, Olson J, Ghosh P, Boss GR, Walker MJ, Cole JN, Nizet V. The conserved surface-associated 5′-nucleotidase of group A Streptococcus is a vaccine antigen that protects against systemic infection.

Sakoulas G, Murray B, Askarian F, Nizet V. Ertapenem and cefazolin synergism in methicillin-susceptible Staphylococcus aureus with type A beta-lactamase.

Corriden R, Döhrmann S, Flores R, Denholtz M, Catteau L, Olson J, Chen A, Carlin AF, Nizet V.   Free fatty acids enhance formation of neutrophil extracellular traps.

Escajadillo T, Popov LM, Dahesh S, Carette JE, Nizet V. Sterol regulatory element binding protein-2 (SREBP-2) influences host cell susceptibility to the bacterial pore-forming toxin streptolysin O.

Sun J, Uchiyama S, Olson J, Cornax I, Ando N, Kohno Y, Kyaw M, Aguilar B, Haste NM, Rose WE, Sakoulas G, Marth JD, Nizet V.  Repurposed drugs block toxin-driven platelet clearance by the hepatic Ashwell-Morell receptor to clear Staphylococcus aureus bacteremia.

Mesci P, LaRock CN, Ferrasa A, Herai RH, Jeziorski J, Saleh A, Trujillo CA, Nizet V, Muotri AR. Impact of human microglial cells on neuronal connectivity during development.

Rada C, Mejia-Pena H, Grimsey N, Canto Cordova I, Olson J, Wozniak J, Gonzalez DJ, Nizet V, Trejo J. Heat Shock Protein 27 activity is linked to endothelial barrier resolution induced by GPCR pro-inflammatory mediators.

Saha S, Coady A, Sasmal A, Kawanishi K, Choudhury B, Yu H, Sorensen R, Inostroza J, Schoenhofen I, Chen X, Münster-Kühnel A, Sato C, Kitajima K, Ram S, Nizet V, Varki A. Ketodeoxynonulosonic acid uptake and surface display by non-typeable Haemophilus influenzae: impairment of bacterial immune evasion and implications for therapeutics.

Askarian F, Uchiyama S, Masson H, Bunaes AC, Golten O, Mekasha S, Røhr ÅK, Kommedal E, Ludviksen JA, Sørenson HV, Arntzen MØ, Schmidt B, van Sorge NM, Eijsink VG, Krengel U, Mollnes TE, Lewis NE, Nizet V, Vaaje-Kolstad G. The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection.

Machado H, Seif Y, Sakoulas G, Olson CA, Szubin R, Palsson BO, Nizet V, Feist AM. Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus.

Kumaraswamy M, Coady A, Szubin R, Martin TC, Palsson BO, Nizet V, Monk JM. Comprehensive whole genome sequencing with hybrid assembly of a multi-drug resistant Candida albicans isolate causing cerebral abscess

Seif Y, Poudel S, Tsunemoto H, Rajput A, Szubin R, Meehan MJ, Olson CA, Alarcon G, Lamsa A, Dillon N, Vrbananc A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, Pogliano J, Feist AM, Palsson BO, Nizet V. Profiling the effect of nafcillin on HA-MRSA D592 using bacteriological and physiological media.  BioRxiv

Sastry AV, Dillon N, Poudel S, Hefner Y, Xu S, Szubin R, Feist A, Nizet V, Palsson BO. Decomposition of transcriptional responses provides insights into differential antibiotic susceptibility.  BioRxiv

Machado H, Seif Y, Sakoulas G, Olson CA, Szubin R, Palsson BO, Nizet V, Adam M, Feist A. Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus.

Rajput A, Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Seif Y, Lamsa A, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, Pogliano P, Nizet V, Feist AM, Palsson BO. Identifying the effect of vancomycin on HA-MRSA strains using bacteriological and physiological media. BioRxiv

Dillon N, Seif Y, Tsunemoto H,  Poudel S, Meehan MJ,  Szubin R, Olson CA, Rajput A, Alarcon G, Lamsa A, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, Feist AM, Pogliano P, Palsson BO, Nizet V. Characterizing the response of Acinetobacter baumannii ATCC 17978 to azithromycin in multiple in vitro growth conditions.  BioRxiv

Bjanes E, Nizet V. More than a pore: non-lytic antimicrobial functions of complement and bacterial strategies for evasion.

Hirose Y, Yamaguchi M, Sumitomo T, Nakata M, Hanada T, Okuzaki D, Motooka D, Mori Y, Kawasaki H, Amagai M, Nizet V, Kawabata S. Streptococcus pyogenes upregulates arginine metabolism to exert its pathogenesis on the skin surface.

Lum G, Mercado V, van Ens D, Nizet V, Kimmey JM, Patras KA. Hypoxia-inducible factor 1 alpha is dispensable for host defense of group B Streptococcus colonization and infection.

Gao NJ, Uchiyama S, Pill L, Dahesh S, Olson J, Bautista L, Maroju S, Berges A, Liu JZ, Zurich RH, van Sorge NM, Fairman F, Kapoor N, Nizet V. Novel group A streptococcal cell wall polyrhamnose-SpyAD protein conjugate for use in polyvalent vaccines.

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